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安徽中医药大学药学院导师介绍：杨晔

杨晔，女，1982年5月出生，博士，副教授，2005年获武汉大学药学专业医学学士和生命科学专业理学学士，2010年获西南交通大学材料学专业药物缓控释及组织工程研究方向博士学位。

一、目前在研课题

1．安徽省自然科学基金“载盐酸青藤碱自溶性微针制备技术及经皮吸收性能研究”（项目编号11040606M219），第二

2．安徽中医学院自然基金“核壳微/纳米粒子型新藤黄酸靶向给药系统的研究”，主持

3．安徽中医学院博士后启动基金

二、主要研究方向

① 药物缓控释系统

② 纳米及复合材料

③ 组织工程皮肤

三、近五年发表论文：

1．Yang Y, Xia T, Zhi W, Wei L, Weng J, Zhang C, Li X. Promotion of skin regeneration in diabetic rats by electrospun core-sheath fibers loaded with basic fibroblast growth factor. Biomaterials. 2011, 32: 4243-4254. (IF 7.882)

2．Yang Y, Li X, Cheng L, He S, Zou J, Chen F, Zhang Z. Core–sheath structured fibers with pDNA polyplex loadings for the optimal release profile and transfection efficiency as potential tissue engineering scaffolds. Acta Biomater. 2011, 7: 2533-2543. (IF 4.822)

3．Yang Y, Li X, He S, Cheng L, Chen F, Zhou S, Weng J. Biodegradable ultrafine fibers with core-sheath structures for protein delivery and its optimization. Polym Advan Technol. doi: 10.1002/pat.1681. (IF 1.776)

4．Yang Y, Zhu X, Cui W, Li X, Jin Y. Electrospun composite mats of poly(D,L-lactide)-co-glycolide and collagen with high porosity as potential scaffolds for skin tissue engineering. Macromol Mater Eng. 2009, 294: 611-619. (IF 1.916)

5．Yang Y, Li X, Cui W, Zhou S. Structural stability and release profiles of proteins from core-shell poly (DL-lactide) ultrafine fibers prepared by emulsion electrospinning, J Biomed Mater Res A. 2008, 86: 374-385. (IF 3.044)

6．Yang Y, Li X, Qi M, Zhou S, Weng J. Release pattern and structural integrity of lysozyme encapsulated in core-sheath structured poly(DL-lactide) ultrafine fibers prepared by emulsion electrospinning. Eur J Pharm Biopharm. 2008, 69: 106-116. (IF 4.304)

7．Zou J, Yang Y, Liu Y, Chen F, Li X. Release kinetics and cellular profiles for bFGF-loaded electrospun fibers: Effect of the conjugation density and molecular weight of heparin. Polymer 52 (2011) 3357-3367.

8．Qi M, Li X, Yang Y, Zhou S. Electrospun fibers of acid-labile biodegradable polymers containing ortho ester groups for controlled release of paracetamol. Eur J Pharm Biopharm. 2008, 70: 445-452.

9．Cui W, Zhu X, Yang Y, Li X, Jin Y. Evaluation of electrospun fibrous scaffolds of poly(DL-lactide) and poly(ethylene glycol) for skin tissue engineering. Mater Sci Eng C. 2009, 29: 1869-1876.

10．Xie C, Li X, Luo X, Yang Y, Cui W, Zou J, Zhou S. Release modulation and cytotoxicity of hydroxycamptothecin-loaded electrospun fibers with 2-hydroxypropyl-β-cyclodextrin inoculations. Int J Pharm. 2010, 391: 55-64.

四、联系方式

电话：5169224

邮箱：gnayye@126.com

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